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Effects of Fasting and Phoenix dactylifera on the Expression of Major Drug-Metabolizing Enzymes in the Mouse Livers

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Israa University
Balasmeh R.; Jarrar Y.; Al-Sheikh I.; Alshaiah H.; Jarrar Q.; Alani R.; Abudahab S.
Balasmeh, Ruba (57998718700); Jarrar, Yazun (57070259300); Al-Sheikh, Iyad (57202691267); Alshaiah, Hamza (57998740300); Jarrar, Qais (56786465300); Alani, Raad (57685907100); Abudahab, Sara (57209986949)
57998718700; 57070259300; 57202691267; 57998740300; 56786465300; 57685907100; 57209986949
2022
Current Drug Metabolism
Effects of Fasting and Phoenix dactylifera on the Expression of Major Drug-Metabolizing Enzymes in the Mouse Livers
23
8
666
676
Bentham Science Publishers
Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan; Department of Pharmaceutical Science, Al-Isra'a University, Amman, Jordan; Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Rich-mond, VA, United States
Balasmeh R., Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan; Jarrar Y., Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan; Al-Sheikh I., Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan; Alshaiah H., Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan; Jarrar Q., Department of Pharmaceutical Science, Al-Isra'a University, Amman, Jordan; Alani R., Department of Pharmaceutical Science, Al-Isra'a University, Amman, Jordan; Abudahab S., Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University, Rich-mond, VA, United States
Y. Jarrar; Department of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan; email: yazun.jarrar@zuj.edu.jo
5
10.2174/1389200223666220820105330
aging; Drug-metabolizing enzymes; fasting; intermittent-fasting; mRNA expression; Phoenix dactylifera
Animals; Chromatography, Liquid; Male; Mice; Phoeniceae; Plant Extracts; RNA, Messenger; Tandem Mass Spectrometry; cytochrome P450 3A11; drug metabolizing enzyme; Phoenix dactylifera extract; plant extract; unclassified drug; messenger RNA; plant extract; acute toxicity; animal experiment; animal model; Article; date (fruit); fasting; food intake; gene expression; gene expression profiling; histology; histopathology; LD50; liquid chromatography-mass spectrometry; mouse; mRNA expression level; nonhuman; physical examination; phytochemistry; protein expression; real time polymerase chain reaction; RNA extraction; toxicity testing; upregulation; animal; liquid chromatography; male; Phoenix (plant); tandem mass spectrometry